About the binding(s?) and missing folios

[Jorge_Stolfi]

Another possibility is that the Painter noticed that the drawing of You are not allowed to view links. Register or Login to view. extended into f40r, and thus opened the book on that page and painted those bits.  It seems that the paint on You are not allowed to view links. Register or Login to view. stops a hair before the gutter, and the paint on You are not allowed to view links. Register or Login to view. does not quite match:

I struggle to imagine that painting while the manuscript is bound would yield such clean result ; colour right up to the margin, while not covering neither the opposite page f34r, nor the binding string visible on You are not allowed to view links. Register or Login to view. (first flower from the top). It also seems to me that the bottom part of the middle flower shows paint right into the gutter

But on the top flower the paint seems to stop a pixel or two before the gutter (A):
   
Also the offsetting of the blue-black paint on You are not allowed to view links. Register or Login to view. (B,C) seems to be vertically mismatched relative to paint on f33v.  What do we make of that?

And could please someone explain what we see at (D,E)?  Is that binding string running along the gutter? 

All the best, --stolfi