Everything about "pox leber" as a minced oath, and an earlier source.

[Koen G]

My understanding is that "pox" as a disease is an English thing, and you wouldn't expect that in German. I may be wrong, but I think the plural form in -en prevents this.

The word order would be alright, you could have something "blatern vertreiben" or whatever, so the disease could be the first word of the sentence. But as much as I'd like that to work for poxleber, I don't think it does.